Use of cerny epoxides for the accelerated synthesis of glycosaminoglycans.
نویسندگان
چکیده
[reaction: see text]. 1,6:2,3-Dianhydrohexopyranoses (Cerny epoxides) are versatile intermediates for the synthesis of glycosaminoglycans. Complex heparan and chondroitin sulfate disaccharide synthons can be assembled from a single common precursor in a short sequence of steps.
منابع مشابه
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1,4-bis(triphenylphosphonium)-2-butene dichloride was developed as a new phase transfer catalyst. This quaternized phosphonium salt catalyzed the regioselective ring opening of epoxides by thiocyanate ion to give β-hydroxy thiocyanates in high yields under mild conditions.
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ورودعنوان ژورنال:
- Organic letters
دوره 5 22 شماره
صفحات -
تاریخ انتشار 2003